A novel, simple method for enrichment of enantiomeric excess of scalemic 1,1'-bi-2-naphthol

Venkatraman, Lakshmanan ; Periasamy, Mariappan (1996) A novel, simple method for enrichment of enantiomeric excess of scalemic 1,1'-bi-2-naphthol Tetrahedron: Asymmetry, 7 (9). 2471-2474 . ISSN 0957-4166

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/095741...

Related URL: http://dx.doi.org/10.1016/0957-4166(96)00309-6

Abstract

Enantiomeric excess of scalemic (i.e nonracemic, 17–86% ee) 1,1'-bi-2-naphthol are readily enhanced to 90–96% ee by refluxing with B(OH)3 and TMEDA in acetonitrile, followed by acid hydrolysis of the precipitate.

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