Structure of metformin hydrochloride

Hariharan, M. ; Rajan, S. S. ; Srinivasan, R. (1989) Structure of metformin hydrochloride Acta Crystallographica Section C, 45 . pp. 911-913. ISSN 0108-2701

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Official URL: http://scripts.iucr.org/cgi-bin/paper?fe0015

Related URL: http://dx.doi.org/10.1107/S0108270188014246

Abstract

N,N-Dimethylbiguanide hydrochloride, C4H12N5.Cl, Mr=165.6, monoclinic, P21/a, a=7.991(3), b=13.950(5), c=8.020(2)Å, β=114.98(3)°, V=810.4(5)Å3, Z=4, Dm=1.35(1), Dx=1.357Mgm-3, MoKα, λ=0.7107Å, μ=0.41mm-1, T=295K, F(000)=352.0, R=0.038 and wR=0.032 for 980 observed reflections with I>3σ(I). The protonation occurs at one of the imino groups and the molecules are stabilized by means of N—H···Cl and N—H···N types of hydrogen bond.

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