On the nature of growth inhibition of Escherichia coli by an oxidation product of vitamin B₁₂

Abstract

1. An oxidation product of vitamin B₁₂ inhibits growth of E. coli (Macleod). 2. Of various substances tried, it is observed that yeast extract, peptone, E. coli crushed cells extract or a mixture of amino acids, overcome growth inhibition of the B₁₂ oxidation product to an appreciable extent. 3. The amino acids when tried individually are found to be inactive.