Niflumic acid in the management of rheumatoid and osteoarthritis

Abstract

Nifumic acid in the dosage of 250 mg four times a day and Phenyl butazone 100 nag four times a day were given to 30 classical cases of rheumatoid arthritis and 10 cases of osteoarthritis in a de-signed double blind cross over trial to find out the efficacy and side effects o f niflumic acid. It was revealed that niflumic acid is a potent, safe and non-steroidal anti-inflammatory agent, by different indices and para-meters used in the study. It was noted to be a better anti-inflam­matory agent than phenylbutazone in patient's own assessment, functional status and relief of pain. It is practically devoid of side effects and with excellent gastric tolerance.