Factor and rifampicin influencing RNA polymerase isolated from chromatin of eukaryotic cell

Mondal, H. ; Mandal, R. K. ; Biswas, B. B. (1970) Factor and rifampicin influencing RNA polymerase isolated from chromatin of eukaryotic cell Biochemical and Biophysical Research Communications, 40 (5). pp. 1194-1200. ISSN 0006-291X

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000629...

Related URL: http://dx.doi.org/10.1016/0006-291X(70)90922-8

Abstract

Two RNA-polymerases (I and II) and several protein fractions (A, B and C) have been isolated from chromosomal acidic proteins of coconut nuclei. Fraction B stimulates the activity of both the RNA-polymerases and appears to be an initiation factor. RNA-polymerase I is sensitive to rifampicin when the drug is added to the enzyme first before the addition of factor B, but insensitive when the order of addition is reversed. Fraction C has an inhibitory effect on both the RNA-polymerases.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:3558
Deposited On:12 Oct 2010 04:15
Last Modified:19 May 2011 08:45

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