Search for physiologically active compounds. Part XII. Synthesis and fungistatic activity of 5:6- and 5:8-quinoline quinone

Harinath Babu, B. ; Subba Rao, N. V. (1968) Search for physiologically active compounds. Part XII. Synthesis and fungistatic activity of 5:6- and 5:8-quinoline quinone Proceedings of the Indian Academy of Sciences, Section A, 67 (1). pp. 31-36. ISSN 0370-0089

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Official URL: http://www.ias.ac.in/j_archive/proca/67/1/31-36/vi...

Related URL: http://dx.doi.org/10.1007/BF03049931

Abstract

A few 5:6- and 5:8-quinoline quinones have been synthesised by oxidising the corresponding aminohydroxy and diaminoquinolines. The required aminohydroxy quinolines could be prepared by nitrosation of hydroxy quinolines and subsequent reduction. Coupling the monoamino quinolines with diazotised sulphanilic acid and reduction afforded the diamino quinolines. 6:7-dichloro- and 6:7-dibromo-5:8-quinoline quinones exhibited fungistatic activity nearly equal to that of 2:3-dichloro-1:4-naphthoquinone.

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ID Code:33732
Deposited On:30 Mar 2011 12:26
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