Vilsmeier-Haack reaction of 1-methyl-34-dihydroisoquino lines-unexpected formation of 2,3-bisdimethylamino-5,6-dihydropyrrolo [2,1-a]isoquinolines

Nagarajan, Kuppuswamy ; Rodrigues, Patrick J. ; Nethaji, Munirathinam (1992) Vilsmeier-Haack reaction of 1-methyl-34-dihydroisoquino lines-unexpected formation of 2,3-bisdimethylamino-5,6-dihydropyrrolo [2,1-a]isoquinolines Tetrahedron Letters, 33 (47). pp. 7229-7232. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(00)60880-8

Abstract

Novel pyrroloisoquinolines 4̲ are obtained from 1-methyl-3,4-dihydroisoquinolines 1̲ by the action of POCl3 and DMF, along with the expected mono- and dialdehydes 2̲ and 3̲ respectively and also directly from N-acetyl-2-phenethylamines.

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