Crystalline constituents of euphorbiaceae-V: New lignans from Phyllanthus niruri Linn.- the constitution of phyllanthin

Ramachandra Row, L. ; Srinivasulu, C. ; Smith, M. ; Subba Rao, G. S. R. (1966) Crystalline constituents of euphorbiaceae-V: New lignans from Phyllanthus niruri Linn.- the constitution of phyllanthin Tetrahedron, 22 (8). pp. 2899-2908. ISSN 0040-4020

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4020(01)99083-0

Abstract

An improved method for the isolation of phyllanthin and hypophyllanthin from the leaves of Phyllanthus niruri Linn. has been described. Their molecular formulae have been revised as C24H34O6 and C24H30O7. The structure of phyllanthin is now shown to be (+)3,4,3′,4′,9,9′-hexamethoxy-8:8'-butyrolignan (IV) from its reactions and degradation to veratric acid. NMR spectra of phyllanthin and its derivatives support this structure.

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Deposited On:07 Apr 2011 13:52
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