Crystalline constituents of euphorbiaceae—XII: Isolation and structural elucidation of three new lignans from the leaves of Phyllanthus niruri Linn.

Anjaneyulu, A. S. R. ; Jaganmohan Rao, K. ; Ramachandra Row, L. ; Subrahmanyam, C. (1973) Crystalline constituents of euphorbiaceae—XII: Isolation and structural elucidation of three new lignans from the leaves of Phyllanthus niruri Linn. Tetrahedron, 29 (10). pp. 1291-1298. ISSN 0040-4020

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4020(01)83146-X

Abstract

Three more new lignans from the hexane extract of Phyllanthus niruri Linn. are now reported besides phyllanthin and hypophyllanthin. The structure of niranthin is now established as 3,3',4',9,9'-pentamethoxy-4,5-methylenedioxy-8,8'-butyrolignan (2). Nirtetralin and phyltetralin are shown to be 1-phenyl tetralins. On the basis of NMR and mass spectra, nirtetralin is assigned the structure (7) and phyltetralin (11).

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