15N-NMR spectra of azoles with two heteroatoms

Chen, Ban Chin ; Philipsborn, Wolfgang Von ; Nagarajan, Kuppuswamy (1983) 15N-NMR spectra of azoles with two heteroatoms Helvetica Chimica Acta, 66 (5). pp. 1537-1555. ISSN 0018-019X

Full text not available from this repository.

Official URL: http://onlinelibrary.wiley.com/doi/10.1002/hlca.19...

Related URL: http://dx.doi.org/10.1002/hlca.19830660522


The 15N-NMR spectra of azoles, with natural isotope abundance, have been measured under different experimental conditions, and chemical shifts are reported for imidazoles, pyrazoles, oxazoles, isoxazoles, thiazoles, and isothiazoles. General trends of substituent effects in this heterocyclic series are discussed based on the data of 67 substituted azoles, dihydro- and tetrahydroazoles. 15N, 1H spin-coupling constants have been determined from spectra obtained by [1H] → 15N polarizationtransfer experiments, i.e. an application of INEPT and DEPT pulse sequences. Two-bond and three-bond coupling constants are fully assigned and are discussed in terms of the specific pathways in azoles. The potential of structural applications of the new data is illustrated for isomeric nitro-imidazoles and highly-substituted pyrazoles, and in the case of ring-chain tautomerism of 2-substituted tetrahydrooxazoles.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
ID Code:33259
Deposited On:21 Mar 2011 14:23
Last Modified:21 Mar 2011 14:23

Repository Staff Only: item control page