Histidine α-deaminase activity in the stratum corneum of the human in normal and vitamin B12/folate deficiency states

Satwekar, K. ; Radhakrishnan, A. N. ; Baker, S. J. (1968) Histidine α-deaminase activity in the stratum corneum of the human in normal and vitamin B12/folate deficiency states Clinica Chimica Acta, 20 (1). pp. 53-59. ISSN 0009-8981

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000989...

Related URL: http://dx.doi.org/10.1016/0009-8981(68)90384-7

Abstract

Histidine α-deaminase activity of the stratum corneum has been measured in normal subjects and in patients with vitamin B12 and folate deficiency. The enzyme levels in the patients were significantly lower than in the controls. Enzyme levels returned to normal following treatment with vitamin B12 and/or folic acid. Some of the implications of these findings are discussed. The Wellcome Trust in association with the World Health Organization. Abbreviations employed: Folic acid: F.A.; Vitamin B12:B12.

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