Screening of HLA antibodies in maternal sera from Hyderabad

Naik, Pradeep ; Indira, S. ; Pitchappan, R. M. ; Malati, T. (1991) Screening of HLA antibodies in maternal sera from Hyderabad Indian Journal of Clinical Biochemistry, 6 (2). pp. 119-123. ISSN 0970-1915

Full text not available from this repository.

Official URL:

Related URL:


Antibodies against human leucocyte antigens (HLA) in sera from uni and multiparous women are the potential source of HLA reagent. The present study was undertaken to screen 169 sera from pregnant women for the presence of HLA antibodies employing 26 panel cells (Peripheral blood lymphocytes) having known HLA phenotypes. 20.7% (35/169) sera were found to be positive for HLA class-1 antibodies. Present study generated one monospecific, (r=0.6 for A32) the duospecific sera (r=0.5 for A2 B35, r=0.47 A1 DR6 and r=0.7 A28 B51), and rest multispecific sera (r=below 0.4). These positive sera will be utilized as HLA reagents in future studies for tissue typing.

Item Type:Article
Source:Copyright of this article belongs to Association of Clinical Biochemistry of India.
ID Code:31921
Deposited On:25 Apr 2011 13:29
Last Modified:25 Apr 2011 13:29

Repository Staff Only: item control page