Synthesis of 3-coumaryl phenyl sulfones or sulfoxides

Merchant, J. R. ; Shah, P. J. (1981) Synthesis of 3-coumaryl phenyl sulfones or sulfoxides Journal of Heterocyclic Chemistry, 18 (2). pp. 441-442. ISSN 0022-152X

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/jhet.55...

Related URL: http://dx.doi.org/10.1002/jhet.5570180249

Abstract

An unambiguous synthesis of a number of 3-coumaryl phenyl sulfones or sulfoxides have been described which were obtained by the oxidation of the corresponding sulfides with hydrogen peroxide. The sulfides were prepared by the Perkin-Oglialore reaction of o-hydroxyaldehyde with the sodium salt of different S-phenyl thioacetic acids. The sulfones did not exhibit any appreciable antitubercuious activity in the preliminary screening tests.

Item Type:Article
Source:Copyright of this article belongs to Journal of Heterocyclic Chemistry.
ID Code:31724
Deposited On:30 Mar 2011 12:11
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