A new and efficient general method for the synthesis of 2-spirobenzopyrans: first synthesis of cyclic analogues of precocene I and related compounds

Dike, Suneel Y. ; Merchant, Jayasukhlal R. ; Sapre, Niteen Y. (1991) A new and efficient general method for the synthesis of 2-spirobenzopyrans: first synthesis of cyclic analogues of precocene I and related compounds Tetrahedron, 47 (26). pp. 4775-4786. ISSN 0040-4020

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4020(01)86481-4

Abstract

A new synthesis of spirobenzopyran has been accomplished by Friedel-Crafts reaction of various m-dihydroxybenzenes and cycloalkylidene acetic acid in the presence of a Lewis acid. Starting from cycloalkylidene acetic acid novel synthesis of 2-spiro-benzopyrans has been accomplished.

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