[Ru(phen)2(dppz)]2+ as an efficient optical probe for staining nuclear components

Rajendiran, Venugopal ; Palaniandavar, Mallayan ; Periasamy, Vaiyapuri Subbarayan ; Akbarsha, Mohammad Abdulkader (2010) [Ru(phen)2(dppz)]2+ as an efficient optical probe for staining nuclear components Journal of Inorganic Biochemistry, 104 (2). pp. 217-220. ISSN 0162-0134

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S01620...

Related URL: http://dx.doi.org/10.1016/j.jinorgbio.2009.10.018

Abstract

The 'molecular light switch' complexes [Ru(bpy)2(dppz)]2+ (1) and [Ru(phen)2(dppz)]2+ (2), where bpy = 2,2'-bipyridine, phen = 1,10-phenanthroline and dppz = dipyrido[3,2-a:2',3'-c]phenazine, have been explored as probes for diagnosing and staining nuclear components. The phen complex acts as a better staining agent for nonviable cells than for viable cells and exhibits a staining efficiency in tail region of comet more specific and stronger than the already known dye Hoechst 33258.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Ru(II) Complexes; Nuclear Staining Agents; Bio-imaging; Comet Assay
ID Code:31016
Deposited On:27 Dec 2010 06:47
Last Modified:05 Mar 2011 04:46

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