Timely administration of melatonin accelerates reentrainment to phase-shifted light-dark cycles in the field mouse mus booduga

Chandrashekaran, Maroli K. ; Sharma, Vijay Kumar ; Singaravel, Muniyandi ; Subbaraj, Ramanujam (1999) Timely administration of melatonin accelerates reentrainment to phase-shifted light-dark cycles in the field mouse mus booduga Chronobiology International, 16 (2). pp. 163-170. ISSN 0742-0528

Full text not available from this repository.

Official URL: http://informahealthcare.com/doi/ref/10.3109/07420...

Related URL: http://dx.doi.org/10.3109/07420529909019083

Abstract

The effect of melatonin on the rate of reentrainment after a 6h phase delay and a 6h phase advance in the light-dark (LD) cycle was assayed in the nocturnal field mouse Mus booduga. After a phase delay of 6h in the LD cycle, a single dose of melatonin (1 mg/kg) was administered for three consecutive days at about CT4 (circadian time 4). After a phase advance of 6h in the LD cycle, melatonin was administered for three consecutive days at about CT22. Melatonin was found to accelerate reentrainment in both cases. Melatonin-treated animals took significantly fewer cycles to reentrain compared to vehicle-treated (50% dimethylsulfoxide [DMSO]) and nontreated control animals.

Item Type:Article
Source:Copyright of this article belongs to Informa Healthcare.
Keywords:Circadian; Melatonin; Reentrainment; Phase shift
ID Code:30757
Deposited On:27 Dec 2010 08:19
Last Modified:05 Dec 2012 07:04

Repository Staff Only: item control page