Clinical evaluation of a new anthelmintic-thiabendazole [2-(4'-thiazolyl)-benzimidazole]

Salunkhe, D. S. ; Gaitonde, B. B. ; Vakil, B. J. (1964) Clinical evaluation of a new anthelmintic-thiabendazole [2-(4'-thiazolyl)-benzimidazole] The American Journal of Tropical Medicine and Hygiene, 13 (3). pp. 412-416. ISSN 0002-9637

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Thiabendazole administered to 61 patients with intestinal helminthiasis in single doses of 1.25 or 2.5 grams was found to be effective in Ascaris lumbricoides infection in a dose of 1.25 g. Its action against Ancylostoma duodenale was comparable in effectiveness to 2 g of bephenium or 3 ml of tetrachlorethylene, on the basis of mean percentage reduction in egg-count. It had no marked effect on Trichuris trichiura infection. In a dose of 2.5 g it produced giddiness and vomiting.

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ID Code:30303
Deposited On:22 Dec 2010 09:55
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