Effects of tin on sulfhydryl containing enzymes in liver of rats

Dwivedi, R. S. ; Kaur, G. ; Srivestava, R. C. ; Krishna Murti, C. R. (1983) Effects of tin on sulfhydryl containing enzymes in liver of rats Chemosphere, 12 (3). pp. 333-340. ISSN 0045-6535

Full text not available from this repository.

Official URL: http://linkinghub.elsevier.com/retrieve/pii/004565...

Related URL: http://dx.doi.org/10.1016/0045-6535(83)90108-X


A single intraperitoneal administration of tin (II) tartrate to albino rats (2 mg Sn++/100 g body wt) depressed the levels of hepatic glutathione reductase, glucose-6-phosphate dehydrogenase, lactate dehydrogenase, succinic dehydrogenase, reduced glutathione (GSH) and total sulfhydryl contents and led to an elevated level of tin. Serum aminotransferase levels were however, not affected but an increase in serum bilirubin and calcium levels was noticed. studies showed that tin tartrate upto a concentration of 2 uM did not affect the activity of liver enzymes tested, when the enzyme preparations were incubated with metallic salts during the time of assay. The critical concentration of tin for these parameters was at 5 μM.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:29390
Deposited On:17 Dec 2010 08:08
Last Modified:04 Jun 2011 09:06

Repository Staff Only: item control page