Total synthesis of the putative structure of the novel triquinane based sesquiterpenoid natural product dichomitol

Mehta, Goverdhan ; Pallavi, Kotapalli (2006) Total synthesis of the putative structure of the novel triquinane based sesquiterpenoid natural product dichomitol Tetrahedron Letters, 47 (47). pp. 8355-8360. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.09.084

Abstract

A total synthesis of the recently reported triquinane natural product dichomitol, isolated from the fermentation broth of Dichomitus squalens, has been accomplished from the commercially available 1,5-cyclooctadiene through a series of unambiguous synthetic steps. A complete mismatch between the spectral characteristics of the synthetic product and that of the natural product warrants a revision of the structure of dichomitol.

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Deposited On:18 Dec 2010 05:42
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