Total synthesis of the novel NF-kB inhibitor (-)-cycloepoxydon

Mehta, Goverdhan ; Islam, Kabirul (2004) Total synthesis of the novel NF-kB inhibitor (-)-cycloepoxydon Organic Letters, 6 (5). pp. 807-810. ISSN 1523-7060

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An enantioselective total synthesis of the novel, biologically active epoxyquinone natural product (-)-cycloepoxydon has been accomplished from the readily available Diels-Alder adduct of cyclopentadiene and p-benzoquinone. A new cycloepoxydon related heptacyclic dimer has been prepared and characterized.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:28960
Deposited On:18 Dec 2010 05:45
Last Modified:18 Dec 2010 05:45

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