Inhibition of deoxyribonucleic acid replication in Bacillus brevis by ribonucleic acid polymerase inhibitors

Bhattacharya, S. ; Sarkar, N. (1981) Inhibition of deoxyribonucleic acid replication in Bacillus brevis by ribonucleic acid polymerase inhibitors Journal of Bacteriology, 145 (3). pp. 1442-1444. ISSN 0021-9193

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Official URL: http://jb.asm.org/cgi/content/abstract/145/3/1442

Abstract

The incorporation of [3H]thymidine into deoxyribonucleic acid by exponentially growing cells of bacillus brevis was inhibited by streptolydigin and rifampin in the same concentration range in which these drugs inhibit ribonucleic acid synthesis. Complete inhibition occurred within one-third generation time after drug addition, suggesting an effect on deoxyribonucleic acid chain elongation.

Item Type:Article
Source:Copyright of this article belongs to American Society for Microbiology.
ID Code:2855
Deposited On:09 Oct 2010 05:41
Last Modified:16 May 2016 13:45

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