Characterisation of cell-wall-derived polypeptide antigens from different species of mycobacterium

Babu, Susan ; Jain, N. K. ; Prasad, G. ; Bhattacharya, Sudha ; Bhattacharya, A. (1990) Characterisation of cell-wall-derived polypeptide antigens from different species of mycobacterium Journal of Medical Microbiology, 32 . pp. 263-269. ISSN 0022-2615

[img]
Preview
PDF - Publisher Version
1MB

Official URL: http://jmm.sgmjournals.org/cgi/content/abstract/32...

Related URL: http://dx.doi.org/10.1099/00222615-32-4-263

Abstract

Cell walls from different species of mycobacterium were purified on a sucrose step gradient. The components derived from these preparations were characterised by sodium dodecyl sulphate-polyacrylamide gel electrophoresis, followed by staining or by western blotting. Surface-exposed polypeptide molecules were also identified by biotinylation. Many protein and glycoprotein molecules were identified in the cell walls. Some of these molecules were immunogenic in man and experimental animals and showed wide variability from species to species. The data suggest that these molecules could be of significance in the diagnosis and pathophysiology of mycobacterial diseases.

Item Type:Article
Source:Copyright of this article belongs to Society for General Microbiology.
ID Code:2836
Deposited On:09 Oct 2010 05:45
Last Modified:16 May 2016 13:44

Repository Staff Only: item control page