Cardiovascular effects of serotonin on the pigeon Columba livia

Banerjee, D. ; Ghosh, Asok (1984) Cardiovascular effects of serotonin on the pigeon Columba livia Proceedings of the Indian Academy of Sciences - Animal Sciences, 93 (3). pp. 199-202. ISSN 0253-4118

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The effect of serotonin on the blood pressure and the heart rate of the pigeon Columba livia was investigated in anaesthetised condition. The effect of histamine was also investigated to understand the mechanism of action of serotonin. Serotonin and histamine were both depressors. Serotonin produced bradycardia while histamine produced tachycardia. Atropine treatment reversed the serotonin-induced depressor response but only partially blocked the histamine-induced fall in blood pressure. Atropine treatment completely abolished the serotonin-induced bradycardia but partially inhibited the histamine-induced tachycardia. A reflex vagal activity and a direct vasoconstrictor activity were proposed on the action of serotonin.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:Serotonin; Histamine; Blood Pressure; Heart Rate; Atropin; Columba livia
ID Code:28037
Deposited On:15 Dec 2010 12:34
Last Modified:17 May 2016 11:14

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