C4 null alleles in a swedish population

Nityanand, S. ; Dawkins, R. L. ; Lithell, H. ; Holm, G. ; Lefvert, A. K. (1995) C4 null alleles in a swedish population International Journal of Immunogenetics, 22 (6). pp. 435-441. ISSN 1744-3121

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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1744-...

Related URL: http://dx.doi.org/10.1111/j.1744-313X.1995.tb00281.x


The distribution of C4 null alleles (C4Q0) was studied in a Swedish population comprising 410 male individuals from Stockholm County and Uppsala City. The prevalances of homozygous C4A*Q0 and C4B*Q0 determined by analysing the gene products in serum were 5.0 and 5.6%, respectively, in the Stockholm population and 4.0% each in the Uppsala population. These values are higher than those previously reported from other Caucasian populations. The finding reflects a different genetic composition of the Swedish population and may have relevance to the disease spectrum in this population as compared to other Caucasian populations.

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ID Code:27173
Deposited On:08 Dec 2010 12:35
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