Kinetics of serotonin in platelets in essential hypertension

Nityanand, Soniya ; Tekwani, B. L. ; Chandra, Mahesh ; Shanker, Kirpa ; Singh, B. N. (1990) Kinetics of serotonin in platelets in essential hypertension Life Sciences, 46 (5). pp. 367-372. ISSN 0024-3205

Full text not available from this repository.

Official URL:

Related URL:


In a study of the kinetics of 5-hydroxytryptamine (5-HT) in platelets in 26 hypertensive subjects with a mean systolic and diastolic blood pressure of 153.9 ± 26.9 and 106.9 ± 9.1 mm Hg respectively, it has been observed that in hypertensive platelets there was a marked decrease in 5-HT uptake and content, an increase in 5-HT efflux and an accompanying increase in Plasma 5-HT and 5-HIAA levels. Regression analysis of the data indicated a significant correlation between rise in diastolic blood pressure and these changes in 5-HT kinetics.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:27164
Deposited On:08 Dec 2010 12:36
Last Modified:08 Dec 2010 12:36

Repository Staff Only: item control page