Reduction of triterpenoid ketones with bornan-2-exo-yloxyaluminium dichloride: a convenient preparation of axial triterpene alcohols

Nasipuri, Dhanonjoy ; Mukherjee, Pranab R. ; Pakrashi, Satyesh C. ; Datta, Supreeti ; Ghosh-Dastidar, Partha P. (1976) Reduction of triterpenoid ketones with bornan-2-exo-yloxyaluminium dichloride: a convenient preparation of axial triterpene alcohols Journal of the Chemical Society, Perkin Transactions 1 (3). pp. 321-323. ISSN 0300-922X

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Official URL: http://www.rsc.org/publishing/journals/P1/article....

Related URL: http://dx.doi.org/10.1039/P19760000321

Abstract

Reduction of 3-oxo-triterpenoids with bornan-2-exo-yloxyaluminium dichloride furnishes axial (3 α-) alcohols as the major products (75-100%), which are easily separable from the reaction mixtures. Reduction with sodium borohydride gives mainly the 3α-alcohols (85-95%).

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