Mapping the common antigenic determinants in avidin and streptavidin

Subramanian, N. ; Adiga, P. Radhakantha (1997) Mapping the common antigenic determinants in avidin and streptavidin IUBMB Life, 43 (2). pp. 375-382. ISSN 1521-6543

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Official URL: http://www3.interscience.wiley.com/journal/1178886...

Related URL: http://dx.doi.org/10.1080/15216549700204161

Abstract

An epitope scan analysis of the whole sequence of avidin and core streptavidin using polyclonal antibodies to these two antigens reveal the presence of multiple common epitopes in both the proteins. These antigenic determinants consist mostly of either identical or similar residues. The antibody recognition sites in both antigens are shown to be localized to homologous regions.

Item Type:Article
Source:Copyright of this article belongs to International Union of Biochemistry and Molecular Biology.
Keywords:Common Epitopes; Biotin-binders; Antibodies; Localization
ID Code:26780
Deposited On:08 Dec 2010 13:12
Last Modified:13 May 2011 04:10

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