Effect of heparin on wound healing

Tarvady, Sandhya ; Anguli, V. C. ; Pichappa, C. V. (1987) Effect of heparin on wound healing Journal of Biosciences, 12 (1). pp. 33-40. ISSN 0250-5991

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Official URL: http://www.ias.ac.in/jarch/jbiosci/12/33-40.pdf

Related URL: http://dx.doi.org/10.1007/BF02716951


Heparin with its ability to dissolve the fibrin clot exerts its major effect in the early stages of wound healing by depriving the fibroblasts of their scaffold. Heparin inhibits cross linking of collagen and accelerates its degradation. There is faulty orientation of the collagen fibrils in the heparinized wound. It may be concluded that heparin interferes with wound healing.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:Heparin; Collagen; Glycosaminoglycans; Wound Healing
ID Code:26731
Deposited On:08 Dec 2010 13:19
Last Modified:17 May 2016 10:02

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