Strand breaks in deoxyribonucleic acid of thymine-starved bacteria

Bhattacharjee, Sukhendu B. ; Das, Jyotirmoy (1973) Strand breaks in deoxyribonucleic acid of thymine-starved bacteria International Journal of Radiation Biology, 23 (2). pp. 167-174. ISSN 0955-3002

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Official URL: http://informahealthcare.com/doi/abs/10.1080/09553...

Related URL: http://dx.doi.org/10.1080/09553007314550181

Abstract

Thymine starvation of E. coli B/r resulted in a decrease in single-strand molecular weight of DNA, as determined by sedimentation in alkaline sucrose gradient. This decrease could not be compensated by 60 min incubation in growth medium after thymine starvation. The strand breaks in DNA induced by x-irradiation could not be repaired in growth medium in 60 min when the cells were prestarved of thymine. Thymine-starved cells also showed more strand breaks in DNA, at the same levels of survival, due to x-irradiation than the cells that were not so starved.

Item Type:Article
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ID Code:26585
Deposited On:08 Dec 2010 13:32
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