Repair of ultraviolet-light-induced DNA damage in Vibrio cholerae

Das, Goutam ; Sil, Kaveri ; Das, Jyotirmoy (1981) Repair of ultraviolet-light-induced DNA damage in Vibrio cholerae Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 655 (3). pp. 413-420. ISSN 0005-2787

Full text not available from this repository.

Official URL:

Related URL:


Repair of ultraviolet-light-induced DNA damage in a highly pathogenic Gram-negative bacterium, Vibrio cholerae, has been examined. All three strains of V. cholerae belonging to two serotypes, Inaba and Ogawa, are very sensitive to ultraviolet irradiation, having inactivation cross-sections ranging from 0.18 to 0.24 m2/J. Although these cells are proficient in repairing the DNA damage by a photoreactivation mechanism, they do not possess efficient dark repair systems. The mild toxinogenic strain 154 of classical Vibrios presumably lacks any excision repair mechanism and studies of irradiated cell DNA indicate that the ultraviolet-induced pyrimidine dimers may not be excised. Ultraviolet-irradiated cells after saturation of dark repair can be further photoreactivated.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:DNA Repair; Ultraviolet Irradiation; Dark Repair; Photoreactivation; (Vibrio cholerae)
ID Code:26556
Deposited On:08 Dec 2010 13:34
Last Modified:09 Feb 2011 08:38

Repository Staff Only: item control page