Ray, Manju ; Bhaduri, Amar (1975) Udpglucose 4-epimerase from saccharomyces fragilis : desensitization with heat Biochemical and Biophysical Research Communications, 67 (3). pp. 877-882. ISSN 0006-291X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000629...
Related URL: http://dx.doi.org/10.1016/0006-291X(75)90758-5
Abstract
The allosteric kinetics exhibited by UDP glucose 4-epimerase from Saccharomyces fragilis changes over to a normal hyperbolic kinetics when the enzyme is heated at 41° for 2 mins. The native enzyme is completely insensitive to inhibition by UMP in the allosteric region. The desensitized enzyme is however, strongly inhibited by UMP at this low concentrations. Apparently, desensitization by heat converts the enzyme to its ultimate catalytic form.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 26440 |
| Deposited On: | 06 Dec 2010 12:32 |
| Last Modified: | 16 May 2011 10:27 |
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