Indications for penetrating keratoplasty in India

Dandona, L. ; Ragu, K. ; Janarthanan, M. ; Naduvilath, T. J. ; Shenoy, R. ; Rao, G. N. (1997) Indications for penetrating keratoplasty in India Indian Journal of Opthamology, 45 (3). pp. 163-168. ISSN 0301-4738

Full text not available from this repository.

Official URL:


Indications for penetrating keratoplasty (PK) in the developing world from a large series are not well documented. This study was done to evaluate the indications for PK in a major eye care institution in India. The records for a consecutive series of 1,964 PKs were analysed and multiple logistic regression was used to study the effect of age, socioeconomic status and sex on the indications for PK. The indications for PK were corneal scarring in 551 (28.1%) including adherent leukoma in 147 (7.5%), regrafts in 336 (17.1%), active infectious keratitis in 239 (12.2%), aphakic bullous keratopathy in 231 (11.8%), pseudophakic bullous keratopathy in 209 (10.6%), corneal dystrophies in 165 (8.4%) including Fuchs' dystrophy in 23 (1.2%), keratoconus in 118 (6%), and miscellaneous in 115 (5.9%). The odds that the patient belonged to lower socioeconomic status were significantly higher if the PK was done for active infectious keratitis (odds ratio 2.73, p<0.0001), corneal scarring (odds ratio 1.72, p=0.0009) or regraft (odds ratio 1.44, p=0.047). Corneal scarring, including adherent leukoma, and active infectious keratitis are relatively more common indications whereas keratoconus, pseudophakic bullous keratopathy and Fuchs' dystrophy are less common indications for PK in India than reported from the developed world. Indications for PK which carry a poorer prognosis for graft survival are relatively more common in India than in the developed world.

Item Type:Article
Source:Copyright of this article belongs to All India Ophthalmological Society.
Keywords:Penetrating Keratoplasty; Indications; Developing World
ID Code:24976
Deposited On:01 Dec 2010 12:22
Last Modified:08 Jun 2011 06:44

Repository Staff Only: item control page