4-alkoxy-3-cyano-2(1H)-pyridones and 5-alkoxyisoxazoles and their aryl substituted and annulated derivatives from acylketene O,S-acetals

Purkayastha, Makhan L. ; Bhat, Laxminarayan ; Ila, Hiriyakkanavar ; Junjappa, Hiriyakkanavar (1995) 4-alkoxy-3-cyano-2(1H)-pyridones and 5-alkoxyisoxazoles and their aryl substituted and annulated derivatives from acylketene O,S-acetals Synthesis, 1995 (6). pp. 641-643. ISSN 0039-7881

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-1995-3974

Abstract

The title pyridones 2 and 5 and the isoxazoles 3 are obtained in moderate to good yields by cyclocondensation of the appropriate acylketene O,S-acetals 1 or 4 with cyanoacetamide and hydroxylamine hydrochloride, respectively, in the presence of sodium alkoxide/alkanol.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers Inc.
Keywords:Acylketene O,S-acetals; 4-alkoxy-3-cyano-2(1H)-pyridones; 5-alkoxyisoxazoles; Acylketene Dithioacetals; Cyclocondensation
ID Code:24085
Deposited On:29 Nov 2010 10:28
Last Modified:22 Feb 2011 05:21

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