Chattopadhyay, Aindrila ; Choudhury, Tapasi Das ; Basu, Mukul K. ; Datta, Asoke G. (1992) Effect of Cu2+-ascorbic acid on lipid peroxidation, Mg2+-ATPase activity and spectrin of RBC membrane and reversal by erythropoietin Molecular and Cellular Biochemistry, 118 (1). pp. 23-30. ISSN 0300-8177
Full text not available from this repository.
Official URL: http://www.springerlink.com/content/g227735j7uxj35...
Related URL: http://dx.doi.org/10.1007/BF00249691
Abstract
The effect of erythropoietin (Ep), a glycoprotein hormone, has been studied on lipid peroxidation induced by Cu2+ and ascorbate in vitro, Mg2+ ATPase activity and spectrin of RBC membrane. Our present investigation reveals that Cu2+ and ascorbic acid increases lipid peroxidation of RBC membrane significantly. It has further been observed that under the same experimental condition spectrin, a major cytoskeleton membrane protein, and Mg2+-ATPase activity of RBC membrane decrease significantly. However, exogenous administration of Ep completely restores lipid peroxidation and Mg2+-ATPase activity and partially recovers spectrin of RBC membrane.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer-Verlag. |
| Keywords: | Erythropoietin; Lipid Peroxidation; Mg2+-atpase; Cu2+-ascorbic Acid; RBC Membrane; Spectrin |
| ID Code: | 23584 |
| Deposited On: | 26 Nov 2010 08:38 |
| Last Modified: | 30 May 2011 11:36 |
Repository Staff Only: item control page
