Leishmania donovani: assay for a functional pentose phosphate pathway

Ghosh, Dilip K. ; Datta, Asoke G. (1971) Leishmania donovani: assay for a functional pentose phosphate pathway Experimental Parasitology, 29 (1). pp. 103-109. ISSN 0014-4894

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001448...

Related URL: http://dx.doi.org/10.1016/0014-4894(71)90017-8


Respiratory studies with the protozoal organism Leishmania donovani have shown that this organism is capable of utilizing ribose as substrate. Studies with cell-free extract of this organism showed that it is rich in some key enzymes of the pentose phosphate pathway. Carbon dioxide production from glucose-1-14C and glucose-6-14C indicates that in this organism probably the Embden-Meyerhof and Parnas pathway is playing a more important role than the shunt pathway.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Leishmania donovani; Carbohydrates; Metabolism; Pentose Phosphate Pathway; Glucose-6-phosphate Dehydrogenase; Phosphoribose Isomerase; Transketolase; Enzymes; Transaldolase; Carbon Isotopes; Glucose; Manometry; Spectrophotometry; Chromatography
ID Code:23583
Deposited On:26 Nov 2010 08:38
Last Modified:31 May 2011 04:33

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