Haemoglobin phenotypes in water buffalo (Bos bubalus) during development

Ranjekar, P. K. ; Barnabas, J. (1969) Haemoglobin phenotypes in water buffalo (Bos bubalus) during development Comparative Biochemistry and Physiology, 28 (3). pp. 1395-1401. ISSN 0010-406X

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001040...

Related URL: http://dx.doi.org/10.1016/0010-406X(69)90576-3


The water buffalo has two foetal haemoglobins along with small amounts of adult components at birth. The structural differences between the two foetal haemoglobins are located in the α -chains and the two foetal haemoglobin types appear to be α21 γ2 and α211γ 2. Each adult buffalo has two haemoglobins with variant α-chains and which are of α21β 2 and α211β 2 Hb types. During post-natal development, the γ -chain is gradually replaced by the β -chain, the concentrations of α1 and α11 chains remaining, more or less, constant. A duplcation of the α-chain gene followed by mutation is assumed to account for the presence of two variant α-chain genes which are expressed together in each water buffalo from birth through maturity.

Item Type:Article
Source:Copyright of this article belongs to Canadian Society of Zoologists.
Keywords:Foetal Haemoglobins; Buffalo (Bos bubalus); Protein Chains; Polymorphism of Proteins; Haemoglobin; Phenotype
ID Code:2331
Deposited On:07 Oct 2010 09:50
Last Modified:13 May 2011 09:07

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