Evolution of hemoglobin in primates and other therian mammals

Barnabas, John ; Goodman, Morris ; Moore, G. William (1971) Evolution of hemoglobin in primates and other therian mammals Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 39 (3). pp. 455-482. ISSN 0305-0491

Full text not available from this repository.

Official URL: http://linkinghub.elsevier.com/retrieve/pii/030504...

Related URL: http://dx.doi.org/10.1016/0305-0491(71)90192-1


1. 1. Phylogenetic trees of twenty-seven alpha and thirty-four betalike mammalian hemoglobin chains and thirty-seven vertebrate globin chains were constructed from amino-acid sequence data. 2. 2. Highlighting the phyletic closeness of African apes to man, the trees provided detailed information on patterns of globin-gene evolution among mammals. 3. 3. Ancestral amino-acid sequences were deduced and mutation distances from branching points in the mammalian beta and alpha trees to descendant sequences calculated. 4. 4. Less alpha and beta change in the descent of higher primates than other mammals was demonstrated and possible selective mechanisms discussed.

Item Type:Article
Source:Copyright of this article belongs to Canadian Society of Zoologists.
Keywords:Hemoglobin Evolution; Gene Phylogenetic Trees; Mutation Distances; Unweighted Pair Group Method; Dendograms; Amino-acid Sequences; Primates; Therian Mammals; Anthropoidea; Gene Duplication; Unequal Homologous Crossing Over; Ungulates; African Apes; Deceleration of Molecular Evolution; Placentas; Maternal Isoimmunization; alpha Globin Chains; beta-like Globin Chains; Neutral Mutations; Natural Selection
ID Code:2326
Deposited On:07 Oct 2010 09:52
Last Modified:07 Oct 2010 09:52

Repository Staff Only: item control page