Glucosamine-6-phosphate deaminase activity during connective tissue growth

Sekhara Varma, T. N. ; Bachhawat, B. K. (1963) Glucosamine-6-phosphate deaminase activity during connective tissue growth Biochimica et Biophysica Acta, 69 . pp. 464-471. ISSN 0006-3002

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000630...

Related URL: http://dx.doi.org/10.1016/0006-3002(63)91295-2

Abstract

The presence of glucosamine-6-phosphate deaminase, which reversibly degrades glucosamine 6-phosphate into fructose 6-phosphate and ammonia, has been established in the connective tissue developed by the subcutaneous implantation of cotton pellets. Some of the properties of this enzyme are described. It is observed that carrageenin is without any effect on the induction of the enzyme during the development of the granulomata. Pharmacologically high doses of cortisone, however, inhibit the glucosamine-6-phosphate deaminase activity both in ordinary granulomata and in those induced by carrageenin.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:2244
Deposited On:07 Oct 2010 12:24
Last Modified:14 Jun 2011 09:31

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