Jain, B. ; Dube, A. ; Das, K. ; Gupta, P. K. (2006) pH Dependent binding of chlorin-p6 with phosphatidyl choline liposomes: comparison between one and two-photon excited fluorescence Chemical Physics Letters, 426 (1-3). pp. 163-167. ISSN 0009-2614
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00092...
Related URL: http://dx.doi.org/10.1016/j.cplett.2006.05.113
Abstract
The relative changes in the fluorescence intensities of chlorin-p6 upon binding to phosphatidyl choline liposomes were observed to be different for one-photon (400 nm) and two-photon (800 nm) excitation at pH 5.0, 6.0 and 7.4. The corresponding fluorescence lifetimes however, were found to be similar. This is attributed to the higher two-photon absorption cross-section of the lipid bound drug. Measurements made on the changes in the lipid bound drug's fluorescence on variation of the lipid:drug molar ratio reveals that two-photon excitation might be more useful for differentiating between the free and lipid bound drug.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 22253 |
| Deposited On: | 23 Nov 2010 08:34 |
| Last Modified: | 02 Jun 2011 06:48 |
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