Occurrence of flavokinase activity in plants

Giri, K. V. ; Krishnaswamy, P. R. ; Appaji Rao, N. (1957) Occurrence of flavokinase activity in plants Nature, 179 . pp. 1134-1135. ISSN 0028-0836

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Official URL: http://www.nature.com/nature/journal/v179/n4570/ab...

Related URL: http://dx.doi.org/10.1038/1791134b0


Riboflavin functions biologically as either flavin mononucleotide or flavin-adenine-dinucleotide, which constitute the prosthetic group of a variety of enzymes. A study of pathways through which these nucleotides themselves are synthesized from the free vitamin would be valuable. The only reports in the literature regarding the enzymatic synthesis of flavin mononucleotide pertain to the study of the enzyme from baker's yeast and a riboflavin-excreting mutant yeast BY2. On the basis of the specificity and stoichiometry of the reaction, the enzyme was designated 'flavokinase'. In this communication, the occurrence of the enzyme in plants is reported for the first time.

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