Inbreeding and post-natal mortality in South India: effects on the gene pool

Buttles, A. H. ; Devi, A. Radha Rama ; Savithri, H. S. ; Sridhar, Rajeshwari ; Appaji Rao, N. (1985) Inbreeding and post-natal mortality in South India: effects on the gene pool Journal of Genetics, 64 (2-3). pp. 135-142. ISSN 0022-1333

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Consanguineous marriages have been favoured throughout South India for many generations. On theoretical grounds it was proposed that long-term inbreeding would have resulted in the elimination of deleterious, recessive lethal and sub-lethal genes. As part of a newborn screening programme for amino acidopathies, data were collected on the level of inbreeding in the current populations of the cities of Bangalore and Mysore, and on the relationship between consanguinity and mean numbers of liveborn and living children. Mean cnonsanguinity was 32.24%, equivalent to a cuoefficient of inbreeding in the newborns, F = 00271. There were no significant differences between the various inbreeding classes in the number of liveborn or living children, nor was a significant consanguinity-related effect on the proportion of survivors detectable. In the light of these findings, the effects on the gene pool of multiple generations of inbreeding are discussed.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:South India; Inbreeding; Liveborns; Living Children
ID Code:21268
Deposited On:20 Nov 2010 13:12
Last Modified:17 May 2016 05:29

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