Babu, Ponnusamy ; Maitra, Uday (2005) Synthesis and in vitro cholesterol dissolution by 23- and 24-phosphonobile acids Steroids, 70 (10). pp. 681-689. ISSN 0039-128X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00391...
Related URL: http://dx.doi.org/10.1016/j.steroids.2005.03.008
Abstract
A new class of 23- and 24-phosphonobile acids have been synthesized from bile acid and their in vitro cholesterol-dissolving efficiency have been estimated. 24-Phosphonobile salts (PBSs) are slightly more efficient in solubilizing cholesterol than 23-PBSs and natural bile salts. The cholesterol solubilizing power is influenced by the structure of PBSs, and is considerably reduced with an increase in the bulk pH.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Bile Acids; Cholesterol Dissolution; Gallstone Dissolution; Phosphonobile Acids |
| ID Code: | 21200 |
| Deposited On: | 20 Nov 2010 09:02 |
| Last Modified: | 17 May 2016 05:24 |
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