Diastereoselective reduction of α-keto esters derived from functionalised cholic acid

Maitra, Uday ; Mathivanan, Packiarajan (1994) Diastereoselective reduction of α-keto esters derived from functionalised cholic acid Tetrahedron: Asymmetry, 5 (7). pp. 1171-1174. ISSN 0957-4166

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/095741...

Related URL: http://dx.doi.org/10.1016/0957-4166(94)80149-5

Abstract

The reduction of phenylglyoxalate 2a and pyruvate 2b with LiBH4 in THF at -80°C yield the corresponding α-hydroxy esters with ca. 70% diastereoselectivity. The reduction of phenylglyoxalate 2a and pyruvate 2b with LiBH4 in THF at -80°C yield the corresponding α-hydroxy esters with ca. 70% diastereoselectivity.

Item Type:Article
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Deposited On:20 Nov 2010 09:03
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