Bhattacharya, Santanu ; Sengupta, Saumitra (2004) Palladium-catalyzed alkynylation of aryl halides (Sonogashira reaction) in water Tetrahedron Letters, 45 (47). pp. 8733-8736. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2004.09.131
Abstract
The palladium catalyzed alkynylation of aryl halides (Sonogashira reaction) has been achieved in pure water without any additives or phase transfer catalysts. The reaction, which requires only 0.5 mol % of Pd(PPh3)4 catalyst, is remarkably fast (30 min at 70 °C) producing high yields of the aryl alkyne products.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Sonogashira Reaction; Palladium; Water; Aryl Halides; Alkynylation |
| ID Code: | 21122 |
| Deposited On: | 20 Nov 2010 09:07 |
| Last Modified: | 20 Nov 2010 09:07 |
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