Bhakuni, Vinod ; Gupta, C. M. (1986) Interactions of tuftsin with bovine serum albumin FEBS Letters, 205 (2). pp. 347-350. ISSN 0014-5793
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001457...
Related URL: http://dx.doi.org/10.1016/0014-5793(86)80926-7
Abstract
Interactions of tuftsin (Thr-Lys-Pro-Arg) with bovine serum albumin (BSA) were analysed by fluorescence spectroscopy and circular dichroism. The data show that tuftsin interacts weakly with BSA, but this interaction is considerably enhanced by introducing an apolar substituent at the C-terminus of the tetrapeptide. It is suggested that strong binding of tuftsin to albumin in blood may enhance its macrophage-stimulating activity in vivo.
| Item Type: | Article |
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| Source: | Copyright of this article belongs to Federation of European Biochemical Societies. |
| Keywords: | Tuftsin(blood); Peptide Stability; Albumin; Macrophage |
| ID Code: | 20986 |
| Deposited On: | 20 Nov 2010 09:23 |
| Last Modified: | 17 May 2016 05:14 |
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