Effects of intranasal administration of hormonal steroids on serum testosterone and spermatogenesis in rhesus monkey (Macaca mulatta)

Anand Kumar, T. C. ; Sehgal, A. ; David, G. F. X. ; Bajaj, J. S. ; Prasad, M. R. N. (1980) Effects of intranasal administration of hormonal steroids on serum testosterone and spermatogenesis in rhesus monkey (Macaca mulatta) Biology of Reproduction, 22 (4). pp. 935-940. ISSN 0006-3363

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Official URL: http://www.biolreprod.org/content/22/4/935.short

Related URL: http://dx.doi.org/10.1095/biolreprod22.4.935

Abstract

Spraying estradiol-17β, progesterone or norethisterone intranasally in adult male rhesus monkeys (7.5-11 kg BW) at a daily dose of 30 μg/day for a period of 60 days resulted in a decrease of testicular size, arrest of spermatogenesis and a significant reduction in serum levels of testosterone. No changes were observed in the solvent-treated controls.

Item Type:Article
Source:Copyright of this article belongs to Society for the Study of Reproduction.
ID Code:2069
Deposited On:08 Oct 2010 09:24
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