Bioavailability of progesterone enhanced by intranasal spraying

David, G. F. X. ; Puri, C. P. ; Anand Kumar, T. C. (1981) Bioavailability of progesterone enhanced by intranasal spraying Cellular and Molecular Life Sciences, 37 (5). pp. 533-534. ISSN 1420-682X

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Official URL: http://www.springerlink.com/content/g5412537371k64...

Related URL: http://dx.doi.org/10.1007/BF01986182

Abstract

The bioavailability of progesterone (P) in terms of area under time-concentration curve and maximal concentration in the serum and cerebrospinal fluid was studied in adult ovariectomized rhesus monkeys following the administration of P as a nasal spray, i.v. or i.m. injections, nasal or eye drops. The bioavailability of P in both the body fluids was found to be considerably higher following its being sprayed intranasally.

Item Type:Article
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