The first synthesis of C-terminal biphenyl moiety of vancomycin

Rama Rao, A. V. ; Chakraborty, T. K. ; Joshi, Subodh P. (1992) The first synthesis of C-terminal biphenyl moiety of vancomycin Tetrahedron Letters, 33 (28). pp. 4045-4048. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/004040...

Related URL: http://dx.doi.org/10.1016/0040-4039(92)88096-N

Abstract

A successful palladium catalysed intramolecular coupling of phenyl rings corresponding to amino acids (R)-4-hydroxyphenylglycine (5̲) and (S)-3,5-dihydroxyphenylglycine (7̲) of vancomycin is achieved.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Vancomycin; Pd-catalysed Biaryl Coupling; Asymmetric Strecker Synthesis;
ID Code:20646
Deposited On:20 Nov 2010 13:48
Last Modified:20 May 2011 11:44

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