Cyclic trimer of 5-(aminomethyl)-2-furancarboxylic acid as a novel synthetic receptor for carboxylate recognition

Chakraborty, Tushar K. ; Tapadar, Subhasish ; Kiran Kumar, S. (2002) Cyclic trimer of 5-(aminomethyl)-2-furancarboxylic acid as a novel synthetic receptor for carboxylate recognition Tetrahedron Letters, 43 (7). pp. 1317-1320. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(01)02367-X

Abstract

A novel 18-membered cyclic oligopeptide 1 based on 5-(aminomethyl)-2-furancarboxylic acid (2), is developed as an excellent receptor for carboxylate binding having an association constant of 8.64×103 M-1 for tetrabutylammonium acetate in CD3CN. The synthesis of 1 was achieved by a high-yielding cyclotrimerization reaction of the unfunctionalized furan amino acid 2.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Cyclic Peptides; Furan Amino Acid; Synthetic Receptors; Molecular Recognition
ID Code:20602
Deposited On:20 Nov 2010 13:53
Last Modified:22 May 2011 15:45

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