Synthesis of chiral 1,3-diols by radical-mediated regioselective opening of 2,3-epoxy alcohols using cp2TiCl

Chakraborty, Tushar K. ; Das, Sanjib (2002) Synthesis of chiral 1,3-diols by radical-mediated regioselective opening of 2,3-epoxy alcohols using cp2TiCl Tetrahedron Letters, 43 (12). pp. 2313-2315. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(02)00241-1

Abstract

Radical-mediated opening of chiral 2,3-epoxy alcohols 1a-e, regioselectively at the 2-position, using cp2TiCl in the absence of a hydrogen source leads to the formation of the 1,3-diols 2a-e.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Epoxy Alcohols; Katsuki-sharpless Reactions; Epoxide Opening; 1,3-diol
ID Code:20601
Deposited On:20 Nov 2010 13:53
Last Modified:22 May 2011 15:44

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